Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1
Sarah Griffith, Luke Muir, Ondrej Suchanek, Joshua Hope, Corinna Pade, Joseph M Gibbons, Zewen Kelvin Tuong, Audrey Fung, Emma Touizer, Chloe Rees-Spear, Andrea Nans, Chloe Roustan, Yilmaz Alguel, Douglas Fink, Chloe Orkin, , Laura E McCoy
The paper isolates a broadly neutralizing HIV-1 antibody from an untreated HIV-1 patient and shows memory B cells remain functional despite viral infection.
bioRxiv · Feb 5, 2024 · PreprintMicrobiology