Zewen Kelvin Tuong

This study develops a subcutaneous tumor model that naturally forms tertiary lymphoid structures (TLS) and identifies CXCL9 as a key regulator of TLS formation and function.

This study shows that keratin76 in the thymus is crucial for central tolerance to skin and oral mucosa antigens, as its loss leads to autoimmune responses.

Single-cell RNA and BCR sequencing of infected mouse spleens shows class switching overlaps clonal expansion, GC-seeding clones also form plasmablasts, and SHM proceeds at constant rate.

This study uses single-cell multi-omics to compare immune cell landscapes and vaccine responses in SAD and CVID patients, identifying unique cellular and molecular features associated with poor vaccination responses.

This study shows that intestinal immunological challenges shape the polarization of dural CD4 T cells, which provide protective memory against pathogens.

The paper integrates single-cell RNA sequencing data across cancer types to resolve cDC2 heterogeneity and identify major DC populations in human tumours.

The paper integrates 12 spatial and single-cell technologies to analyze cellular interactions and signatures in three skin cancers, identifying key therapeutic targets and genetic associations.

R package rebuild for single-cell T/B cell receptor analysis: Rcpp rewrites reportedly make clonal pairing and edit-distance clustering scale linearly; adds auto-detected multi-format import, AIRR-compatible export, CDR3 summaries.

dandelionR provides an R implementation of Dandelion's workflow for analyzing single-cell RNA and immune receptor sequencing data.

The paper isolates a broadly neutralizing HIV-1 antibody from an untreated HIV-1 patient and shows memory B cells remain functional despite viral infection.

The paper constructs a human fetal lung cell atlas from 5-22 post conception weeks, identifying new cell states and regulators of epithelial fates.