Cancer BiologybioRxivPreprint
Selective epithelial expression of KRASG12D mutation drives ductal pancreatic neoplasia in Oncopigs
Carlos P Jara, Al-Murtadha Al-Gahmi, Audrey Lazenby…·Mark A. Carlson
This study uses an Oncopig model to show that selective KRASG12D mutation in pancreatic epithelial cells drives neoplasia and stromal changes similar to human PDAC.
DOI 10.1101/2024.02.01.578513