Author

Aurélie Martinez

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Cell Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Francis RodieriD· 1 shared Guillaume B Cardin· 1 shared Marc Alexandre Olivier· 1 shared Nicolas Malaquin· 1 shared Sabrina Ghadaouia· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Francis RodierORCID

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1 paper

Recent·Most cited

Telomeric dysfunction triggers an unstable growth arrest leading to irreparable genomic lesions and entry into cellular senescence

Sabrina Ghadaouia, Marc Alexandre Olivier, Aurélie Martinez, Nicolas Malaquin, Guillaume B Cardin, Francis Rodier

This study shows that telomere uncapping does not directly trigger senescence but leads to genomic instability through telomere fusions and DNA breaks, resulting in irreversible damage.

bioRxiv · Oct 13, 2018 · PreprintCell Biology