Aging macaques bridge the translational gap in perivascular space biology
William A. Liguore, Daniel L. Schwartz, Juan A. Piantino, Avanthika Rajendran, Greg Jensen, Joshua A. Karpf, Mykyta M. Chernov, Randall L. Woltjer, Steven G. Kohama, Lisa C. Silbert, Alison R. Weiss
This study shows that aging rhesus macaques exhibit age-dependent perivascular space burden, mirroring human patterns, and validates MRI-detected structures as perivascular spaces.
Scientific Reports · Jun 15, 2026Peer-reviewedNeuroscience