Beige fat appearance during lipoatrophy reveals trade-offs between metabolic homeostasis and female fertility
Elizabeth S. Anaya, William A. Dion, Pradip Saha, Aaron R. Cox, Evelyn de Groot, Avery Ahmed, Jessica B. Felix, Bokai Zhu, Stephanie A. Pangas, Sean Michael Hartig
This study shows that lipoatrophy in female mice leads to beige fat recruitment, which improves metabolic outcomes but reduces fertility.
bioRxiv · Apr 21, 2025 · PreprintCell Biology