Author

Aaron R. Cox

Baylor College of MedicineORCID 0000-0002-3330-5746Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Sean Michael HartigiD· 3 shared Jessica B. FelixiD· 2 shared Pradip SahaiD· 2 shared Stephanie A. PangasiD· 2 shared Alexa E. MartineziD· 1 shared Anne Granger· 1 shared Avery Ahmed· 1 shared Bokai ZhuiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

Sean Michael HartigORCID

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4 papers

Recent·Most cited

Beige fat appearance during lipoatrophy reveals trade-offs between metabolic homeostasis and female fertility

Elizabeth S. Anaya, William A. Dion, Pradip Saha, Aaron R. Cox, Evelyn de Groot, Avery Ahmed, Jessica B. Felix, Bokai Zhu, Stephanie A. Pangas, Sean Michael Hartig

This study shows that lipoatrophy in female mice leads to beige fat recruitment, which improves metabolic outcomes but reduces fertility.

bioRxiv · Apr 21, 2025 · PreprintCell Biology

A Comprehensive Atlas of AAV Tropism in the Mouse

Christopher J. Walkey, Kathy J. Snow, Jote Bulcha, Aaron R. Cox, Alexa E. Martinez, M. Cecilia Ljungberg, Denise Grant Lanza, Marco De Giorgi, Marcel A. Chuecos, Michele Alves‐Bezerra, Carlos Perfecto Flores Suarez, Sean Michael Hartig, Susan Galloway Hilsenbeck, Chih‐Wei Hsu, Ethan Saville, , William R. Lagor

This paper maps the tissue tropism of ten AAV serotypes in mice after systemic delivery, identifying liver preference and unexpected transduction in adrenals, testes, and ovaries.

Molecular Therapy · Jan 25, 2025Peer-reviewedMolecular Biology

Ubc9 deletion in adipocytes causes lipoatrophy in mice

Aaron R. Cox, Natasha Chernis, Kang Ho Kim, Peter M. Masschelin, Pradip Saha, Shawn M. Briley, Robert Sharp, Jessica B. Felix, David D. Moore, Stephanie A. Pangas, Sean Michael Hartig

This study shows that deleting Ubc9 in adipocytes causes lipoatrophy and metabolic issues in mice by disrupting adipose tissue expansion and function.

bioRxiv · Sep 12, 2020 · PreprintDevelopmental Biology

Tamoxifen Suppresses Pancreatic β-Cell Proliferation in Mice

Surl-Hee Ahn, Anne Granger, Matthew M. Rankin, Carol J. Lam, Aaron R. Cox, Jake A. Kushner

This study shows that high-dose tamoxifen suppresses β-cell proliferation in mice, with dose-dependent effects and genetic background differences, without affecting glucose homeostasis.

PLoS ONE · Sep 6, 2019Peer-reviewedDevelopmental Biology