Title: Multimodal profiling reveals Mycobacterium tuberculosis restricts lung mitochondrial immunometabolism to promote pathogenesis
Hedwin Kitdorlang Dkhar, Prashant Bajpai, Ana Beatriz Enriquez, Louis Brown Hopkins, Stanzin Dawa, Jonathan Kevin Sia, Ayana Paul, Ranjna Madan-Lala, Mark Cole Keenum, AshishKumar Sharma, Adam Nicolas Pelletier, Shu Ling Goh, Terra Riddick, Ted J. Whitworth, Keith Eric Prater, , Jyothi Rengarajan
This study identifies how M. tuberculosis manipulates lung mitochondrial metabolism to promote pathogenesis and reveals a mitochondrial immunometabolic signature associated with protective immunity.
bioRxiv · Apr 10, 2026 · PreprintImmunology