Author

Azin Kiani

University of Freiburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna-Maria SchafferiD· 1 shared Cabrera MaiaiD· 1 shared Frederike A. HartliD· 1 shared Lena Weiß· 1 shared Maja KöhniD· 1 shared Marina ZintchenkoiD· 1 shared Nadine M. WoessneriD· 1 shared Natalie KöhleriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Anna-Maria SchafferORCID

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1 paper

Recent·Most cited

Controlling TCR and CAR activation by targeting LCK recruitment with a first-in-class small-molecule inhibitor

Nadine M. Woessner, Patricio Chinestrad, Tamina Rückert, Lena Weiß, Marina Zintchenko, Anna-Maria Schaffer, Sara E. Hartmann, Azin Kiani, Maja Köhn, Cabrera Maia, Frederike A. Hartl, Wolfgang W A Schamel, Natalie Köhler, Pablo Lorenzano Menna, Susana Minguet

This study identifies a small-molecule inhibitor that selectively disrupts LCK recruitment to CD3ε, reducing TCR activation while preserving other immune responses.

bioRxiv · Dec 12, 2025 · PreprintImmunology