Cytoskeletal adaptation following long-term dysregulation of actomyosin in neuronal processes
B. A. Cisterna, K. Skruber, M. L. Jane, C. I. Camesi, I. D. Nguyen, P. V. Warp, J. B. Black, M. T. Butler, J. E. Bear, T.-A. Read, E. A. Vitriol
This study shows that long-term actin cytoskeleton dysregulation leads to compensatory changes in microtubules and intermediate filaments in neuronal processes, affecting transport and mimicking neurodegenerative disease features.
bioRxiv · Aug 25, 2023Cell Biology