Author

K. Skruber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

E. A. Vitriol· 4 shared T.-A. Read· 4 shared B. A. Cisterna· 2 shared J. B. Black· 2 shared J. E. Bear· 2 shared M. T. Butler· 2 shared P. V. Warp· 2 shared A. Cherezova· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersCell Biology

E. A. Vitriol

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cytoskeletal adaptation following long-term dysregulation of actomyosin in neuronal processes

B. A. Cisterna, K. Skruber, M. L. Jane, C. I. Camesi, I. D. Nguyen, P. V. Warp, J. B. Black, M. T. Butler, J. E. Bear, T.-A. Read, E. A. Vitriol

This study shows that long-term actin cytoskeleton dysregulation leads to compensatory changes in microtubules and intermediate filaments in neuronal processes, affecting transport and mimicking neurodegenerative disease features.

bioRxiv · Aug 25, 2023Cell Biology

The actin binding protein profilin 1 is critical for mitochondria function

T.-A. Read, B. A. Cisterna, K. Skruber, S. Ahmadieh, H. L. Lindamood, J. A. Vitriol, Y. Shi, A. E. Y. T. Lefebvre, J. B. Black, M. T. Butler, J. E. Bear, A. Cherezova, D. V. Ilatovskaya, N. L. Weintraub, E. A. Vitriol

This study identifies a novel role for profilin 1 in regulating mitochondria function and reveals a potential pathogenic mechanism for ALS-linked PFN1 variants.

bioRxiv · Aug 7, 2023Cell Biology

TDAExplore: quantitative image analysis through topology-based machine learning

P. Edwards, K. Skruber, N. Milicevic, J. B. Heidings, T.-A. Read, P. Bubenik, E. A. Vitriol

TDAExplore uses topology-based machine learning to classify images with fewer samples and provides quantitative group differences and subcellular dissimilarity analysis.

Patterns · Nov 1, 2021Peer-reviewedCell Biology

Profilin 1 Controls the Assembly, Organization, and Dynamics of Leading Edge Actin Structures Through Internetwork Competition and Collaboration

K. Skruber, P. V. Warp, R. Shklyarov, J. D. Thomas, M. S. Swanson, J. L. Henty-Ridilla, T.-A. Read, E. A. Vitriol

This study identifies profilin 1's role in regulating actin network assembly, organization, and dynamics through internetwork competition and collaboration at the leading edge.

bioRxiv · Nov 20, 2019Cell Biology