Structural and functional changes of pyramidal neurons at the site of an implanted microelectrode array in rat primary motor cortex
B. A. Gregory, C. H. Thompson, J. W. Salatino, M. J. Railing, A. F. Zimmerman, B. Gupta, K. Williams, J. A. Beatty, C. L. Cox, E. K. Purcell
This study examines structural and functional changes in pyramidal neurons near implanted microelectrodes in rat motor cortex, finding dendritic disruption, reduced spine density, and altered electrophysiological properties over time.
bioRxiv · Sep 15, 2022 · PreprintBioengineering