Author

E. K. Purcell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:electrophysiology· 2 Organism:rat· 2 Assay:imaging· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

J. W. Salatino· 2 shared A. F. Zimmerman· 1 shared A. P. Kale· 1 shared B. A. Gregory· 1 shared B. Gupta· 1 shared B. Hunt· 1 shared B. Patel· 1 shared C. H. Thompson· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBioengineering

J. W. Salatino

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3 papers

Recent·Most cited

Structural and functional changes of pyramidal neurons at the site of an implanted microelectrode array in rat primary motor cortex

B. A. Gregory, C. H. Thompson, J. W. Salatino, M. J. Railing, A. F. Zimmerman, B. Gupta, K. Williams, J. A. Beatty, C. L. Cox, E. K. Purcell

This study examines structural and functional changes in pyramidal neurons near implanted microelectrodes in rat motor cortex, finding dendritic disruption, reduced spine density, and altered electrophysiological properties over time.

bioRxiv · Sep 15, 2022 · PreprintBioengineering

A Spatial Transcriptomics Study of the Brain-Electrode Interface in Rat Motor Cortex

Q. A. Whitsitt, B. Patel, B. Hunt, E. K. Purcell

This study uses spatial transcriptomics to analyze gene expression changes in rat motor cortex after electrode implantation, identifying 5811 differentially expressed genes across timepoints.

bioRxiv · Dec 3, 2021 · PreprintBioengineering

Alterations in ion channel expression surrounding implanted microelectrode arrays in the brain

J. W. Salatino, A. P. Kale, E. K. Purcell

The paper investigates changes in ion channel expression around brain microelectrode arrays over time and links these changes to signal loss.

bioRxiv · Jan 11, 2019 · PreprintBioengineering