Prebiotic proanthocyanidins inhibit bile reflux-induced esophageal adenocarcinoma through reshaping the gut microbiome and esophageal metabolome
K. M. Weh, C. L. Howard, Y. Zhang, B. A. Tripp, J. Clarke, A. B. Howell, J. H. Rubenstein, J. Abrams, M. Westerhoff, L. A. Kresty
This study shows that prebiotic proanthocyanidins inhibit reflux-induced esophageal adenocarcinoma by altering gut microbiome and esophageal metabolome, reducing inflammation and cellular damage.
bioRxiv · Aug 22, 2023Cancer Biology