J. H. Rubenstein

Prebiotic proanthocyanidins inhibit bile reflux-induced esophageal adenocarcinoma through reshaping the gut microbiome and esophageal metabolome

This study shows that prebiotic proanthocyanidins inhibit reflux-induced esophageal adenocarcinoma by altering gut microbiome and esophageal metabolome, reducing inflammation and cellular damage.

Barrett's esophagus is the precursor of all esophageal adenocarcinomas

This study uses a computational model to show that all esophageal adenocarcinoma cases in the US can be explained by Barrett's esophagus, both diagnosed and undiagnosed, supporting targeted screening efforts.

Optimal timing for cancer screening and adaptive surveillance using mathematical modeling

This paper uses mathematical modeling to optimize cancer screening timing and adaptive surveillance, finding optimal screening ages for Barrett's esophagus patients older than current recommendations.