Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres
T. K. Loe, J. Li, Y. Zhang, B. Azeroglu, M. N. Boddy, E. Lazzerini Denchi
This study shows that PML is required for ALT by localizing the BTR complex to telomeres, and that BTR localization alone can sustain ALT activity.
bioRxiv · Feb 7, 2020Cancer Biology