Ovarian disrupting effects and mechanisms of long- and short-chain per- and polyfluoroalkyl substances in mice
P. Pattarawat, T. Zhan, Y. Fan, J. Zhang, H. Yang, Y. Zhang, S. Moyd, N. C. Douglas, M. Urbanek, B. Buckley, J. Burdette, Q. Zhang, J.-Y. J. Kim, S. Xiao
This study investigates the effects of long- and short-chain PFAS on ovarian function in mice, finding that long-chain PFAS disrupt follicle maturation and ovulation via PPARγ activation.
bioRxiv · Feb 20, 2024 · PreprintPharmacology & Toxicology