Glycyrrhizin, an inhibitor of HMGB1 induces autolysosomal degradation function and inhibits H. pylori infection
U. Khan, B. C. Karmakar, P. Basak, S. Paul, A. Gope, D. Sarkar, A. K. Mukhopadhyay, S. Dutta, S. Bhattacharya
This study shows glycyrrhizin, an HMGB1 inhibitor, restores lysosomal function and reduces H. pylori infection in gastric cells and mice.
bioRxiv · Aug 2, 2022 · PreprintMicrobiology