Author

U. Khan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1

Frequent Co-Authors

B. G. Haddad· 2 shared S. L. Reichow· 2 shared A. Carvidi· 1 shared A. Gope· 1 shared A. Gross· 1 shared A. Hussain· 1 shared A. J. Butte· 1 shared A. K. Mukhopadhyay· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersPhysiology

B. G. Haddad

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Deciphering Cell-types and Gene Signatures Associated with Disease Activity in Rheumatoid Arthritis using Single Cell RNA-sequencing

M. Binvignat, B. Miao, C. Wibrand, M. Yang, D. Rychkov, E. Flynn, J. Nititham, W. Tamaki, U. Khan, A. Carvidi, M. Krueger, E. Niemi, Y. Sun, G. K. Fragiadakis, J. Sellam, , M. Sirota

This study uses single-cell RNA sequencing of PBMCs from RA patients and controls to identify disease-associated cell subsets and gene signatures linked to RA disease activity.

bioRxiv · Oct 5, 2023 · PreprintImmunology

BBIBP-CorV (Sinopharm) vaccination- induced immunity is affected by age, gender and prior COVID-19 and activates responses to spike and other antigens

Z. Hasan, K. I. Masood, S. Qaiser, E. Khan, A. Hussain, Z. Ghous, U. Khan, M. Yameen, I. Hassan, M. I. Nisar, M. F. Qazi, H. A. Memon, S. Ali, S. Baloch, Z. A. Bhutta, , K. Ghias

This study examines how BBIBP-CorV vaccination-induced immunity varies with age, gender, and prior COVID-19, showing differential antibody and T cell responses to SARS-CoV-2 antigens.

bioRxiv · Nov 30, 2022 · PreprintImmunology

Glycyrrhizin, an inhibitor of HMGB1 induces autolysosomal degradation function and inhibits H. pylori infection

U. Khan, B. C. Karmakar, P. Basak, S. Paul, A. Gope, D. Sarkar, A. K. Mukhopadhyay, S. Dutta, S. Bhattacharya

This study shows glycyrrhizin, an HMGB1 inhibitor, restores lysosomal function and reduces H. pylori infection in gastric cells and mice.

bioRxiv · Aug 2, 2022 · PreprintMicrobiology

Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant

J.-J. Tong, U. Khan, B. G. Haddad, P. J. Minogue, E. C. Beyer, V. M. Berthoud, S. L. Reichow, L. Ebihara

This paper investigates the functional and structural properties of a cataract-associated Cx50 mutant, showing it causes enhanced hemichannel currents and cytotoxicity through altered voltage-gating and electrostatic interactions.

bioRxiv · Aug 18, 2021Physiology

Connexin 46 and connexin 50 gap junction channel open stability and unitary conductance are shaped by structural and dynamic features of their N-terminal domains

B. Yue, B. G. Haddad, U. Khan, H. Chen, M. Atalla, Z. Zhang, D. M. Zuckerman, S. L. Reichow, D. Bai

This study investigates how structural and dynamic features of the N-terminal domains of connexin 46 and 50 influence gap junction channel stability and conductance through molecular dynamics simulations and electrophysiology.

bioRxiv · Jul 1, 2020Biophysics