ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming
F. Li, Q. Yuan, W. Di, X. Xia, Z. Liu, N. Mao, L. Li, C. Li, J. He, Y. Li, W. Guo, X. Zhang, Y. Zhu, R. Aji, S. Wang, , D. Gao
The paper identifies ERG's role in prostate cancer by showing it inhibits basal cell differentiation through chromatin interactions, promoting luminal cell fate.
bioRxiv · Apr 3, 2020Cancer Biology