Author

B. Chi-Leon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Bermingham· 1 shared A. Frommlet· 1 shared A. Lingel· 1 shared A. O. Frank· 1 shared A. Ruzin· 1 shared B. Benton· 1 shared C. J. Balibar· 1 shared C. M. Baxter Rath· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Bermingham

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1 paper

Recent·Most cited

Two distinct mechanisms of small molecule inhibition of LpxA acyltransferase essential for lipopolysaccharide biosynthesis

W. Han, X. Ma, C. J. Balibar, C. M. Baxter Rath, B. Benton, A. Bermingham, F. Casey, B. Chi-Leon, M.-K. Cho, A. O. Frank, A. Frommlet, C.-M. Ho, P. S. Lee, M. Li, A. Lingel, , T. Uehara

This study identifies two small-molecule inhibitors of LpxA, revealing distinct inhibition mechanisms and highlighting compound 2's improved properties for antibacterial development.

bioRxiv · Dec 14, 2019 · PreprintBiochemistry