Comparative analysis of genome-wide DNA methylation identifies patterns that associate with conserved transcriptional programs in osteosarcoma
L. J. Mills, M. Scott, P. Shah, A. R. Cunanan, A. Deshpande, B. Auch, B. Curtin, K. B. Beckman, L. G. Spector, A. L. Sarver, S. Subramanian, T. Richmond, J. F. Modiano
This study identifies DNA methylation patterns in human and canine osteosarcoma samples that correlate with conserved transcriptional programs and tumor states, not cell composition.
bioRxiv · Apr 29, 2020Cancer Biology