Author

B. Fakoya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. K. Waldor· 5 shared B. Sit· 4 shared T. Zhang· 3 shared A. Akter· 1 shared A. Zoued· 1 shared C. J. Kuehl· 1 shared D. H. F. Rubin· 1 shared D. R. Leitner· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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5 shared papersMicrobiology

M. K. Waldor

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5 papers

Recent·Most cited

Non-toxigenic Vibrio cholerae challenge strains for evaluating vaccine efficacy and inferring mechanisms of protection

B. Fakoya, K. Hullahalli, D. H. F. Rubin, D. R. Leitner, R. Chilengi, D. Sack, M. K. Waldor

This study develops non-toxigenic V. cholerae challenge strains to evaluate vaccine efficacy and infer protection mechanisms, showing they accurately measure colonization reduction and vibriocidal antibody responses.

bioRxiv · Dec 17, 2021 · PreprintMicrobiology

Proteomic interrogation of the pathogen-host interface in cholera

A. Zoued, H. Zhang, T. Zhang, R. T. Giorgio, C. J. Kuehl, B. Fakoya, B. Sit, M. K. Waldor

The paper investigates the proteomic composition of the pathogen-host interface in cholera using a rabbit model and identifies SP-D as a novel intestinal defense factor.

bioRxiv · Jan 5, 2021 · PreprintMicrobiology

Dissecting serotype-specific contributions to live oral cholera vaccine efficacy

B. Sit, B. Fakoya, T. Zhang, G. Billings, M. K. Waldor

This study evaluates the immunogenicity and protective efficacy of different serotype variants of a live oral cholera vaccine in a germ-free mouse model, finding minimal impact of O1 serotype variation on vaccine function.

bioRxiv · Aug 20, 2020Microbiology

Transient intestinal colonization by a live-attenuated oral cholera vaccine induces protective immune responses in streptomycin-treated mice

B. Fakoya, B. Sit, M. K. Waldor

This study shows that transient intestinal colonization by a live-attenuated cholera vaccine in antibiotic-treated mice induces stronger immune protection than inactivated vaccine.

bioRxiv · May 19, 2020Microbiology

Oral immunization with a probiotic cholera vaccine induces broad protective immunity against Vibrio cholerae colonization and disease in mice

B. Sit, T. Zhang, B. Fakoya, A. Akter, R. Biswas, E. T. Ryan, M. K. Waldor

This study shows that the live-attenuated cholera vaccine HaitiV provides protection against V. cholerae in mice and their offspring through immunological mechanisms, not vaccine transmission.

bioRxiv · Feb 20, 2019Microbiology