Persistent virus-specific and clonally expanded antibody secreting cells respond to induced self antigen in the CNS
A. Agrafiotis, R. Dizerens, I. Vincenti, I. Wagner, R. Kuhn, D. Shlesinger, M. Manero-Carranza, T.-S. Cotet, K.-L. Hong, N. Page, N. Fonta, G. Shammas, A. Mariotte, M. Piccinno, M. Kreutzfeldt, , A. Yermanos
The paper identifies virus-specific, clonally expanded antibody-secreting cells in the CNS that persist and respond to induced self-antigen, with parallels in multiple sclerosis patients.
bioRxiv · Aug 29, 2022Immunology