Author

N. Fonta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:wet-lab / biochemical assay· 2

Frequent Co-Authors

D. Merkler· 3 shared I. Vincenti· 3 shared I. Wagner· 3 shared M. Piccinno· 3 shared N. Page· 3 shared A. Agrafiotis· 2 shared A. Mariotte· 2 shared A. Oxenius· 2 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

D. Merkler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Interleukin-33 from oligodendrocytes sustains effector differentiation of tissue-resident CD8+ T cells and is a druggable target in CNS autoimmune disease

N. Fonta, N. Page, B. Klimek, M. Piccinno, G. Di Liberto, S. Lemeille, M. Kreutzfeldt, A. L. Kastner, Y. I. Ertuna, I. Vincenti, I. Wagner, D. D. Pinschewer, D. Merkler

This study identifies IL-33 from oligodendrocytes as a key regulator of self-reactive CD8+ T cell differentiation in CNS autoimmunity and shows its potential as a therapeutic target.

bioRxiv · Jul 9, 2024 · PreprintImmunology

Myc controls IL-15-driven expansion and translational machinery of NK cells

H. J. Khameneh, N. Fonta, A. Zenobi, C. Niogret, P. Ventura, C. Guerra, I. Kwee, A. Rinaldi, M. Pecoraro, R. Geiger, A. Cavalli, F. Bertoni, E. E. Vivier, A. Trumpp, G. Guarda

This study shows that Myc is essential for NK cell development, expansion, and anticancer immunity by regulating translational machinery and IL-15 responses.

bioRxiv · Dec 20, 2022 · PreprintImmunology

Persistent virus-specific and clonally expanded antibody secreting cells respond to induced self antigen in the CNS

A. Agrafiotis, R. Dizerens, I. Vincenti, I. Wagner, R. Kuhn, D. Shlesinger, M. Manero-Carranza, T.-S. Cotet, K.-L. Hong, N. Page, N. Fonta, G. Shammas, A. Mariotte, M. Piccinno, M. Kreutzfeldt, , A. Yermanos

The paper identifies virus-specific, clonally expanded antibody-secreting cells in the CNS that persist and respond to induced self-antigen, with parallels in multiple sclerosis patients.

bioRxiv · Aug 29, 2022Immunology

Single-cell immune repertoire sequencing of B and T cells in murine models of infection and autoimmunity

D. Shlesinger, K.-L. Hong, G. Shammas, N. Page, I. Sandu, A. Agrafiotis, V. Kreiner, N. Fonta, I. Vincenti, I. Wagner, M. Piccinno, A. Mariotte, B. Klimek, R. Dizerens, M. Manero-Carranza, , A. Yermanos

The paper profiles clonal selection of B and T cells in murine models of infection and autoimmunity using single-cell sequencing, linking repertoire features to cell phenotypes.

bioRxiv · Feb 7, 2022Immunology