Early growth response 2 (EGR2) is a novel regulator of the senescence program
E. J. Tyler, A. Gutierrez Del Arroyo, R. Wallis, B. K. Hughes, J. C. Garbe, M. R. Stampfer, J. Koh, R. Lowe, M. P. Philpott, C. L. Bishop
This study identifies EGR2 as a novel regulator of senescence by activating the ARF and p16 promoters and reversing the senescent phenotype upon its ablation.
bioRxiv · Sep 30, 2020Cell Biology