Author

B. L. Jacobs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

B. G. Hogue· 2 shared G. McFadden· 2 shared K. V. Kibler· 2 shared M. M. Rahman· 2 shared Y. Li· 2 shared A. A. Pinto· 1 shared A. D. Gutierrez-Jensen· 1 shared A. J. Roeder· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

B. G. Hogue

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Effect of exportin 1/XPO1 nuclear export pathway inhibition on coronavirus replication.

M. M. Rahman, B. Estifanos, H. L. Glenn, A. D. Gutierrez-Jensen, K. V. Kibler, Y. Li, B. L. Jacobs, G. McFadden, B. G. Hogue

This study investigates how inhibiting the XPO1 nuclear export pathway affects coronavirus replication in different cell lines, finding varied effects on MHV and SARS-CoV-2.

Viruses · Feb 18, 2025Peer-reviewedMicrobiology

Intranasal immunization with a vaccinia virus vaccine vector expressing pre-fusion stabilized SARS-CoV-2 spike fully protected mice against lethal challenge with the heavily mutated mouse-adapted SARS2-N501YMA30 strain of SARS-CoV-2

K. V. Kibler, M. Szczerba, D. F. Lake, A. J. Roeder, M. Rahman, B. G. Hogue, L. Y. R. Wong, S. Perlman, Y. Li, B. L. Jacobs

bioRxiv · Dec 6, 2021Microbiology

Convergent loss of the necroptosis pathway in disparate mammalian lineages shapes virus countermeasures

A. A. Pinto, L. Q. Alves, F. Neves, G. McFadden, B. L. Jacobs, F. Castro, M. M. Rahman, P. J. Esteves

The paper shows that necroptosis pathway components are lost in multiple mammalian lineages, correlating with viral adaptations that counteract this host defense mechanism.

bioRxiv · Jun 8, 2021Evolutionary Biology