Author
L. Y. R. Wong
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2020-2021 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 29 mutual co-author links4 papers
Recent·Most cited
- DOI 10.3390/vaccines10081172
- MicrobiologybioRxivPreprint
Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19
S. Perlman, L. Y. R. Wong, J. Zheng…·P. B. McCray
This study identifies the PLA2G2D-PGD2/DP1 pathway as a therapeutic target for severe COVID-19 in middle-aged mice, showing protection through DP1 antagonism.
DOI 10.1101/2021.04.20.440676 - MicrobiologybioRxiv
Post-infection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection
C. Dampalla, J. Zheng, K. Perera…·K.-O. Chang
This study shows that post-infection treatment with a deuterated protease inhibitor improves survival and reduces viral load in mice infected with SARS-CoV-2.
DOI 10.1073/pnas.2101555118 - MicrobiologybioRxiv
K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia
S. Perlman, J. Zheng, L. Y. R. WONG…·P. B. McCray
This study uses K18-hACE2 mice to demonstrate severe SARS-CoV-2 infection in lungs and brains, thrombosis in severe cases, and the protective effect of convalescent plasma against lethal disease, while showing anosmia occurs independently of clinical outcome.
DOI 10.1038/s41586-020-2943-z