Author

D. F. Lake

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. J. Roeder· 1 shared B. G. Hogue· 1 shared B. L. Jacobs· 1 shared B. M. Barker· 1 shared C. Jugler· 1 shared D. M. Magee· 1 shared E. A. H. Keppler· 1 shared F. J. Grill· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. J. Roeder

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Volatile metabolites in lavage fluid are correlated to Valley fever disease severity in murine model lung infections

E. A. H. Keppler, M. C. C. Van Dyke, H. L. Mead, D. F. Lake, D. M. Magee, B. M. Barker, H. D. Bean

This study identifies volatile metabolites in murine lung infections correlated with Valley fever disease severity, suggesting potential breath-based diagnostic biomarkers.

bioRxiv · Oct 2, 2022 · PreprintMicrobiology

Humanization and Expression of IgG and IgM Antibodies in Plants as Potential Diagnostic Reagents for Valley Fever

C. Jugler, F. J. Grill, T. E. Grys, D. F. Lake, Q. Chen

This study demonstrates the production of humanized IgG and IgM antibodies in plants for Valley Fever diagnostics, showing they maintain antigen recognition similar to FDA-approved kits.

bioRxiv · Apr 27, 2022Immunology

Intranasal immunization with a vaccinia virus vaccine vector expressing pre-fusion stabilized SARS-CoV-2 spike fully protected mice against lethal challenge with the heavily mutated mouse-adapted SARS2-N501YMA30 strain of SARS-CoV-2

K. V. Kibler, M. Szczerba, D. F. Lake, A. J. Roeder, M. Rahman, B. G. Hogue, L. Y. R. Wong, S. Perlman, Y. Li, B. L. Jacobs

bioRxiv · Dec 6, 2021Microbiology