Rubsicolins are naturally occurring G-protein-biased delta opioid receptor peptides
R. J. Cassell, K. L. Mores, B. L. Zerfas, A. H. Mahmoud, M. A. Lill, D. J. Trader, R. M. van Rijn
The paper identifies naturally occurring rubiscolin peptides that selectively activate G-protein signaling at delta opioid receptors with minimal beta-arrestin recruitment.
bioRxiv · Oct 5, 2018Pharmacology & Toxicology