Author

R. J. Cassell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:plant (other)· 1 Organism:rat· 1

Frequent Co-Authors

K. L. Mores· 2 shared R. M. van Rijn· 2 shared A. H. Mahmoud· 1 shared A. T. Blaine· 1 shared B. L. Zerfas· 1 shared B. R. Cummins· 1 shared D. J. Trader· 1 shared H. Cui· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

K. L. Mores

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2 papers

Recent·Most cited

The Meta-Position of Phe4 in Leu-enkephalin Regulates Potency, Selectivity, Functional Activity, and Signaling Bias at the Delta and Mu Opioid Receptors

R. J. Cassell, K. K. Sharma, H. Su, B. R. Cummins, H. Cui, K. L. Mores, A. T. Blaine, R. A. Altman, R. M. van Rijn

The paper investigates how substituting the meta-position of Phe4 in Leu5-enkephalin affects its binding affinity, signaling bias, and stability at delta and mu opioid receptors.

bioRxiv · Nov 20, 2019Pharmacology & Toxicology

Rubsicolins are naturally occurring G-protein-biased delta opioid receptor peptides

R. J. Cassell, K. L. Mores, B. L. Zerfas, A. H. Mahmoud, M. A. Lill, D. J. Trader, R. M. van Rijn

The paper identifies naturally occurring rubiscolin peptides that selectively activate G-protein signaling at delta opioid receptors with minimal beta-arrestin recruitment.

bioRxiv · Oct 5, 2018Pharmacology & Toxicology