System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion
C. Giannangelo, G. Siddiqui, A. De Paoli, B. M. Anderson, L. E. Edgington-Mitchell, S. A. Charman, D. J. Creek
This paper shows ozonide antimalarials disrupt Plasmodium falciparum haemoglobin digestion, leading to parasite death and stress responses.
PLOS Pathogens · Jun 26, 2020Peer-reviewedMicrobiology