Linear DNA amplicons as a novel cancer vaccine strategy
A. Conforti, E. Salvatori, L. Lione, M. Compagnone, E. Pinto, C. Shorrock, J. A. Hayward, Y. Sun, B. M. Liang, F. Palombo, B. Viscount, L. Aurisicchio
This study develops PCR-produced DNA amplicons as a cancer vaccine strategy, showing they elicit immune responses and reduce tumor growth when combined with immune-checkpoint inhibitors.
bioRxiv · Feb 9, 2022Immunology