Author

M. Compagnone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 5 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Conforti· 5 shared E. Pinto· 5 shared E. Salvatori· 5 shared L. Lione· 5 shared F. Palombo· 4 shared L. Aurisicchio· 4 shared A. Muzi· 3 shared B. Viscount· 3 shared

Activity by Year

2021-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersImmunology

A. Conforti

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Immunogenicity of COVID-eVax Is Moderately Impacted by Temperature and Molecular Isoforms

F. D'Alessio, L. Lione, E. Salvatori, F. Bucci, A. Muzi, G. Roscilli, A. Conforti, M. Compagnone, E. Pinto, G. Battistuzzi, L. Aurisicchio, F. Palombo

This study shows that the immunogenicity of the plasmid DNA vaccine COVID-eVax is not significantly affected by temperature or DNA isoform changes.

bioRxiv · Dec 29, 2022 · PreprintImmunology

A linear SARS-CoV-2 DNA vaccine candidate reduces virus shedding in ferrets

M. Martins, G. M. do Nascimento, A. Conforti, J. C. G. Noll, J. A. Impellizeri, E. Sanches, B. Wagner, L. Lione, E. Salvatori, E. Pinto, M. Compagnone, B. Viscount, J. Hayward, C. Shorrock, L. Aurisicchio, D. G. Diel

This study evaluates a linear SARS-CoV-2 DNA vaccine delivered via electroporation in ferrets, showing reduced virus shedding and immune responses.

bioRxiv · Sep 29, 2022 · PreprintImmunology

A linear DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain elicits protective immunity in domestic cats

A. Conforti, E. Sanchez, E. Salvatori, L. Lione, M. Compagnone, E. Pinto, F. Palombo, Y. Sun, B. Viscount, J. Hayward, C. Shorrock, D. G. Diel, J. A. Impellizeri, L. Aurisicchio

This study evaluates a linear DNA vaccine in domestic cats, showing it is safe and induces immune responses against SARS-CoV-2.

bioRxiv · Jul 20, 2022 · PreprintImmunology

Linear DNA amplicons as a novel cancer vaccine strategy

A. Conforti, E. Salvatori, L. Lione, M. Compagnone, E. Pinto, C. Shorrock, J. A. Hayward, Y. Sun, B. M. Liang, F. Palombo, B. Viscount, L. Aurisicchio

This study develops PCR-produced DNA amplicons as a cancer vaccine strategy, showing they elicit immune responses and reduce tumor growth when combined with immune-checkpoint inhibitors.

bioRxiv · Feb 9, 2022Immunology

The nuts and bolts of SARS-CoV-2 Spike Receptor Binding Domain heterologous expression

M. Maffei, L. C. Montemiglio, G. Vitagliano, L. Fedele, S. Sellathurai, F. Bucci, M. Compagnone, V. Chiarini, C. Exertier, A. Muzi, G. Roscilli, B. Vallone, E. Marra

This paper characterizes the stability and functionality of SARS-CoV-2 RBD produced in three expression systems using biophysical and functional assays.

bioRxiv · Sep 17, 2021Biochemistry

COVID-eVax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19

A. Conforti, E. Marra, F. Palombo, G. Roscilli, M. Rava, V. Fumagalli, A. Muzi, M. Maffei, L. Luberto, L. Lione, E. Salvatori, M. Compagnone, E. Pinto, E. Pavoni, F. Bucci, , De F

This paper evaluates a DNA vaccine candidate, COVID-eVax, which induces strong neutralizing antibodies and T cell responses against SARS-CoV-2 in animal models, showing protective effects against viral challenge.

bioRxiv · Jun 14, 2021 · PreprintImmunology