Author

J. A. Hayward

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

E. Rajendran· 2 shared G. G. van Dooren· 2 shared G. Tachedjian· 2 shared S. M. Zwahlen· 2 shared A. Conforti· 1 shared A. G. Maier· 1 shared A. Johnson· 1 shared A. Nicolas· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

E. Rajendran

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

KoRV-related retroviruses in diverse Australian and African rodent species

J. A. Hayward, G. Tachedjian

This study identifies nine rodent species, including two African rodents, as novel hosts of KoRV-related retroviruses, suggesting rodents as major carriers with a potential origin in Southeast Asia.

bioRxiv · Feb 25, 2024Microbiology

A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites

J. A. Hayward, F. V. Makota, D. Cihalova, E. Rajendran, S. M. Zwahlen, L. Shuttleworth, U. Wiedemann, C. Spry, K. J. Saliba, A. G. Maier, G. G. van Dooren

The paper screens drug-like molecules to identify new electron transport chain inhibitors in apicomplexan parasites, finding chemically diverse compounds effective against resistant strains.

bioRxiv · Feb 13, 2022Microbiology

Linear DNA amplicons as a novel cancer vaccine strategy

A. Conforti, E. Salvatori, L. Lione, M. Compagnone, E. Pinto, C. Shorrock, J. A. Hayward, Y. Sun, B. M. Liang, F. Palombo, B. Viscount, L. Aurisicchio

This study develops PCR-produced DNA amplicons as a cancer vaccine strategy, showing they elicit immune responses and reduce tumor growth when combined with immune-checkpoint inhibitors.

bioRxiv · Feb 9, 2022Immunology

Divergent features of the coenzyme Q:cytochrome c oxidoreductase complex in Toxoplasma gondii parasites

J. A. Hayward, E. Rajendran, S. M. Zwahlen, P. Faou, G. G. van Dooren

This study identifies novel and divergent components of the coenzyme Q:cytochrome c oxidoreductase complex in Toxoplasma gondii, revealing differences from mammalian Complex III.

bioRxiv · Aug 18, 2020Microbiology

Unique Evolution of Antiviral Tetherin in Bats

J. A. Hayward, M. Tachedjian, A. Johnson, A. T. Irving, T. B. Gordon, J. Cui, A. Nicolas, I. Smith, V. Boyd, G. A. Marsh, M. L. Baker, L.-F. Wang, G. Tachedjian

This study characterizes the evolution of tetherin in bats, identifying unique structural variants and splice isoforms with antiviral functions.

bioRxiv · Apr 8, 2020Evolutionary Biology