Unexpected Specificity within Dynamic Transcriptional Protein-Protein Complexes
M. J. Henley, B. M. Linhares, B. S. Morgan, C. A. Fierke, T. Cierpicki, A. Mapp
The paper investigates the molecular recognition of disordered activators by coactivators, revealing that specific contacts and coactivator plasticity drive specificity despite apparent nonspecific interactions.
bioRxiv · May 29, 2020Biochemistry