Characterization of the gastric motility response to human motilin and erythromycin in human motilin receptor-expressing transgenic mice
S. Kato, A. Takahashi, M. Shindo, A. Yoshida, T. Kawamura, K. Matsumoto, B. Matsuura
This study shows that human motilin and erythromycin stimulate gastric motility in human motilin receptor-expressing transgenic mice through Ca2+ influx, suggesting these mice are useful for testing MTLR agonists.
bioRxiv · Oct 5, 2018Pharmacology & Toxicology