Influenza A Virus Negative Strand RNA is Translated for CD8+ T Cell Immunosurveillance
H. Hickman, J. Mays, J. Gibbs, I. Kosik, J. Magadan, K. Takeda, S. Das, G. Reynoso, B. Ngudiankama, J. Wei, J. Shannon, D. McManus, J. Yewdell
This study shows that influenza A virus negative strand RNA can be translated into proteins recognized by CD8+ T cells, challenging the notion that viral negative strands are non-coding.
bioRxiv · Feb 7, 2018Immunology