Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
T. Li, I. Kang, J. Ye, Z. Hu, J. Gibbs, C. Ye, K. Takeda, I. Kosik, G. Shi, J. Holly, M. Kosikova, Z. Ye, A. A. Compton, L. Martinez-Sobrido, R. Johnson, , J. W. Yewdell
This study shows that SARS-CoV-2 syncytia reduce interferon and antibody effectiveness, explaining the evolution of fusogenic viral variants.
bioRxiv · Dec 12, 2023Microbiology
I. Kosik, J. D. S. Santos, M. Angel, Z. Hu, J. Holly, J. S. Gibbs, T. U. Gill, M. Kosikova, T. Li, W. Bakhache, P. T. Dolan, H. Xie, S. F. Andrews, R. A. Gillespie, M. Kanekiyo, , j. yewdell
This study shows that C1q enhances anti-hemagglutinin stem antibody neutralization by blocking viral attachment and expanding the viral escape repertoire.
bioRxiv · Jun 12, 2023 · PreprintMicrobiology
C. Dacon, C. Tucker, L. Peng, C.-C. D. Lee, T.-H. Lin, M. Yuan, Y. Cong, L. Wang, L. Purser, J. K. Williams, C.-W. Pyo, I. Kosik, Z. Hu, M. Zhao, D. Mohan, , J. Tan
The paper identifies six monoclonal antibodies that broadly neutralize coronaviruses by targeting the conserved fusion peptide.
bioRxiv · Apr 11, 2022Immunology
A. D. Lopez-Munoz, I. Kosik, J. Holly, J. W. Yewdell
This study shows SARS-CoV-2 nucleocapsid protein binds to chemokines and modulates immune responses, suggesting it as a target for cross-reactive vaccines.
bioRxiv · Dec 10, 2021Microbiology
H. Zarkoob, A. Allue-Guardia, Y.-C. Chen, O. Jung, A. G. Vilanova, M. Song, J.-G. Park, F. Oladunni, J. Miller, Y.-T. Tung, I. Kosik, D. Schultz, j. yewdell, J. B. Torrelles, L. Martinez-Sobrido, , E. M. Lee
The paper validates in vitro human lung tissue models for studying SARS-CoV-2 and influenza virus infections and antiviral treatments.
bioRxiv · May 11, 2021Microbiology
I. Kosik, D. Angeletti, J. S. Gibbs, M. Angel, K. Takeda, M. Kosikova, V. Nair, H. D. Hickman, H. Xie, C. C. Brooke, J. W. Yewdell
This study shows anti-HA stem antibodies neutralize influenza A virus by inhibiting neuraminidase activity, with implications for therapeutic synergy with NA inhibitors.
bioRxiv · Aug 22, 2018Microbiology
D. Angeletti, I. Kosik, W. T. Yewdell, C. M. Boudreau, V. V. Mallajosyula, M. Chambers, M. Prabhakaran, H. D. Hickman, A. B. McDermott, G. Alter, J. Chaudhuri, J. W. Yewdell
This study shows that immunodominance in influenza HA can be overcome by targeting the conserved stem through specific immunization strategies.
bioRxiv · Jun 14, 2018Immunology
H. Hickman, J. Mays, J. Gibbs, I. Kosik, J. Magadan, K. Takeda, S. Das, G. Reynoso, B. Ngudiankama, J. Wei, J. Shannon, D. McManus, J. Yewdell
This study shows that influenza A virus negative strand RNA can be translated into proteins recognized by CD8+ T cells, challenging the notion that viral negative strands are non-coding.
bioRxiv · Feb 7, 2018Immunology