High glucose attenuates Ca2+ influx in cytotoxic T lymphocytes upon target recognition
H. Zou, G. Schwaer, R. Zhao, D. Alansary, D. Yin, E. C. Schwarz, B. Niemeyer, B. Qu
This study shows high glucose increases store-operated calcium entry but reduces calcium influx during target recognition in CTLs, leading to increased necrosis after killing.
bioRxiv · Apr 9, 2020Immunology