Author

B. O. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

C. C. Torres Caban· 1 shared C. Chatrin· 1 shared C. Lai· 1 shared D. T. Huang· 1 shared E. L. Dearlove· 1 shared E. S. Boyden· 1 shared F. Subach· 1 shared K. D. Piatkevich· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

C. C. Torres Caban

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2 papers

Recent·Most cited

DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids

E. L. Dearlove, C. Chatrin, L. Buetow, S. F. Ahmed, T. Schmidt, M. Bushell, B. O. Smith, D. T. Huang

This study shows that DTX3L ubiquitinates single-stranded DNA and RNA, expanding the known substrates of ubiquitination beyond proteins.

bioRxiv · Apr 2, 2024Biochemistry

Tuning the sensitivity of genetically encoded fluorescent potassium indicators through structure-guided and genome mining strategies

C. C. Torres Caban, M. Yang, C. Lai, L. Yang, F. Subach, B. O. Smith, K. D. Piatkevich, E. S. Boyden

The paper develops genetically encoded fluorescent potassium indicators with tunable binding affinities through structure-guided design and genome mining, showing varying Kd values in vitro and in cells.

bioRxiv · Oct 7, 2021Bioengineering