Author

L. Buetow

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

D. T. Huang· 2 shared A. Roman-Fernandez· 1 shared B. O. Smith· 1 shared C. Chatrin· 1 shared C. Miller· 1 shared D. Bryant· 1 shared D. Strachan· 1 shared E. C. Freckmann· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

D. T. Huang

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Author profile →

2 papers

Recent·Most cited

DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids

E. L. Dearlove, C. Chatrin, L. Buetow, S. F. Ahmed, T. Schmidt, M. Bushell, B. O. Smith, D. T. Huang

This study shows that DTX3L ubiquitinates single-stranded DNA and RNA, expanding the known substrates of ubiquitination beyond proteins.

bioRxiv · Apr 2, 2024Biochemistry

PTEN deficiency exposes a requirement for an ARF GTPase module in integrin-dependent invasion in ovarian cancer.

K. Nikolatou, E. Sandilands, A. Roman-Fernandez, E. M. Cumming, E. C. Freckmann, S. Lilla, L. Buetow, L. McGarry, M. Neilson, R. Shaw, D. Strachan, C. Miller, D. T. Huang, I. A. McNeish, J. C. Norman, , D. Bryant

This study identifies ARF6 as a critical vulnerability in PTEN-deficient ovarian cancer, showing its role in integrin-dependent invasion and its inverse association with patient outcomes.

bioRxiv · Nov 29, 2022Cancer Biology