Author

B. Orr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

H. Maiato· 3 shared F. De Sousa· 2 shared L. T. Ferreira· 2 shared A. C. Figueiredo· 1 shared A. J. Pereira· 1 shared A. M. Gomes· 1 shared C. Ferras· 1 shared C. Guasch Boldu· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

H. Maiato

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Author profile →

3 papers

Recent·Most cited

Misaligned chromosomes that satisfy the spindle assembly checkpoint are a strong predictor of micronuclei formation in dividing cancer cells

A. M. Gomes, B. Orr, M. Novais-Cruz, F. De Sousa, C. Ferras, H. Maiato

The paper shows that chronically misaligned chromosomes satisfying the SAC predict micronuclei formation in cancer cells but not in normal cells.

bioRxiv · Jul 20, 2022Cell Biology

An anaphase surveillance mechanism prevents micronuclei formation from mitotic errors

B. Orr, F. De Sousa, M. Gomes, L. T. Ferreira, A. C. Figueiredo, H. Maiato

This study identifies an Aurora B kinase-mediated mechanism that prevents micronuclei formation by integrating error correction with nuclear envelope reformation during anaphase.

bioRxiv · Feb 26, 2021Cell Biology

Microtubule tyrosination/detyrosination specifies a mitotic error code

L. T. Ferreira, B. Orr, G. Rajendraprasad, A. J. Pereira, C. Lemos, J. T. Lima, C. Guasch Boldu, J. G. Ferreira, M. Barisic, H. Maiato

The paper shows that microtubule tyrosination/detyrosination regulates mitotic error correction by modulating MCAK activity, acting as a mitotic error code.

bioRxiv · Oct 11, 2019Cell Biology