Author

B. P. Klaholz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. G. Myers· 1 shared A. Lechner· 1 shared C. Barchet· 1 shared C. Ciarlo· 1 shared D. Hentsch· 1 shared E. Comer· 1 shared I. Hazemann· 1 shared J. A. Myers· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

A. G. Myers

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Author profile →

3 papers

Recent·Most cited

Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA

S. Holvec, C. Barchet, A. Lechner, L. Frechin, S. N. T. De Silva, I. Hazemann, P. Wolff, O. von Loeffelholz, B. P. Klaholz

The paper presents a 1.9 Å cryo-EM structure of the human 80S ribosome, revealing new rRNA modifications and ions, and their roles in RNA architecture and function.

bioRxiv · Nov 23, 2023 · PreprintBiochemistry

A spectral demixing method for high-precision multi-color localization microscopy

L. Andronov, R. Genthial, D. Hentsch, B. P. Klaholz

This paper introduces a spectral demixing method for multi-color localization microscopy, improving localization precision and chromatic aberration correction.

bioRxiv · Dec 23, 2021Biophysics

Tetracyclines Modify Translation By Targeting Key Human rRNA Substructures.

J. D. Mortison, M. Schenone, J. A. Myers, Z. Zhang, L. Chen, C. Ciarlo, E. Comer, S. K. Natchiar, S. A. Carr, B. P. Klaholz, A. G. Myers

This study identifies tetracyclines as targeting human rRNA substructures, modifying translation and activating the ISR, which correlates with their anti-proliferative effects in cancer cells.

bioRxiv · Feb 1, 2018Cell Biology