Author

S. K. Natchiar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. G. Myers· 1 shared A. Schepartz· 1 shared B. P. Klaholz· 1 shared C. Ciarlo· 1 shared E. Comer· 1 shared F. A. Cruz Navarrete· 1 shared I. Knudson· 1 shared J. A. Myers· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. G. Myers

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2 papers

Recent·Most cited

β-amino acids reduce ternary complex stability and alter the translation elongation mechanism

F. A. Cruz Navarrete, W. C. Griffin, Y.-C. Chan, M. I. Martin, J. L. Alejo, S. K. Natchiar, I. Knudson, R. B. Altman, A. Schepartz, S. J. Miller, S. C. Blanchard

This study investigates how β-amino acid isomers affect ternary complex stability and translation elongation by analyzing their impact on ribosome function and EF-Tu interactions.

bioRxiv · Feb 24, 2024Biochemistry

Tetracyclines Modify Translation By Targeting Key Human rRNA Substructures.

J. D. Mortison, M. Schenone, J. A. Myers, Z. Zhang, L. Chen, C. Ciarlo, E. Comer, S. K. Natchiar, S. A. Carr, B. P. Klaholz, A. G. Myers

This study identifies tetracyclines as targeting human rRNA substructures, modifying translation and activating the ISR, which correlates with their anti-proliferative effects in cancer cells.

bioRxiv · Feb 1, 2018Cell Biology