ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL
G. Wutz, B. T. G. St. Hilaire, R. Ladurner, R. Stocsits, K. Nagasaka, B. Pignard, A. Sanborn, W. Tang, C. Varnai, M. Ivanov, S. Schoenfelder, P. van der Lelij, X. Huang, G. Duernberger, E. Roitinger, , J. M. Peters
The paper shows that ESCO1 and CTCF protect cohesinSTAG1 from WAPL, enabling long chromatin loops that persist during G1-phase.
bioRxiv · Sep 23, 2019Cell Biology