Author

P. van der Lelij

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

G. Wutz· 2 shared A. Sanborn· 1 shared A. Schlattl· 1 shared B. Pignard· 1 shared B. T. G. St. Hilaire· 1 shared C. P. Santos· 1 shared C. Varnai· 1 shared E. L. Aiden· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

G. Wutz

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL

G. Wutz, B. T. G. St. Hilaire, R. Ladurner, R. Stocsits, K. Nagasaka, B. Pignard, A. Sanborn, W. Tang, C. Varnai, M. Ivanov, S. Schoenfelder, P. van der Lelij, X. Huang, G. Duernberger, E. Roitinger, , J. M. Peters

The paper shows that ESCO1 and CTCF protect cohesinSTAG1 from WAPL, enabling long chromatin loops that persist during G1-phase.

bioRxiv · Sep 23, 2019Cell Biology

Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts

P. van der Lelij, S. Lieb, J. Jude, G. Wutz, C. P. Santos, K. Falkenberg, A. Schlattl, J. Ban, R. Schwentner, T. Hoffmann, H. Kovar, F. X. Real, T. Waldman, M. Pearson, N. Kraut, , M. P. Petronczki

The paper identifies a synthetic lethal relationship between STAG1 and STAG2 in cancers, showing STAG1 inactivation selectively targets STAG2-mutated cancer cells.

bioRxiv · Jun 25, 2017Cancer Biology