Functional anatomy of the full length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis
B. S. Stephens, T. Ngo, I. Kufareva, T. M. Handel
A systematic structure-guided mutagenesis study of chemokine receptor CXCR4 reveals novel insights into epitopes regulating ligand recognition, ligand specificity and CXCL12-mediated signaling.
bioRxiv · Jan 21, 2020Pharmacology & Toxicology