Author

B. Strome

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:protein folding & dynamics· 2 Assay:protein sequence· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:diffusion model· 1

Frequent Co-Authors

A. M. Moses· 2 shared A. Moses· 1 shared A. P. Amini· 1 shared A. X. Lu· 1 shared E. Lash· 1 shared G. Peng· 1 shared I. Pritisanac· 1 shared I. S. Hsu· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersEvolutionary Biology

A. M. Moses

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Author profile →

3 papers

Recent·Most cited

Protein generation with evolutionary diffusion: sequence is all you need

S. Alamdari, N. Thakkar, R. van den Berg, N. Tenenholtz, B. Strome, A. Moses, A. X. Lu, N. Fusi, A. P. Amini, K. K. Yang

This paper introduces EvoDiff, a diffusion model that generates diverse, high-fidelity proteins in sequence space, overcoming limitations of structure-based models.

bioRxiv · Sep 11, 2023 · PreprintBioengineering

A functionally divergent intrinsically disordered region underlying the conservation of stochastic signaling

I. S. Hsu, B. Strome, E. Lash, N. Robbins, L. Cowen, A. M. Moses

The paper shows that functionally divergent intrinsically disordered regions in Crz1 enable conserved stochastic signaling through stabilizing selection.

bioRxiv · Jun 1, 2021Evolutionary Biology

Identifying molecular features that are associated with biological function of intrinsically disordered protein regions

T. Zarin, B. Strome, G. Peng, I. Pritisanac, J. D. Forman-Kay, A. M. Moses

The paper identifies molecular features in intrinsically disordered protein regions that predict functional roles and validates their importance in mitochondrial targeting.

bioRxiv · Jun 23, 2020Cell Biology