N. Thakkar

Silversol (a colloidal nanosilver formulation) inhibits growth of antibiotic-resistant Staphylococcus aureus by disrupting its physiology in multiple ways

Silversol inhibits antibiotic-resistant Staphylococcus aureus growth by disrupting multiple physiological processes and altering gene expression related to virulence and metal homeostasis.

Deciphering the molecular mechanisms underlying anti-pathogenic potential of a polyherbal formulation Enteropan against multi-drug resistant Pseudomonas aeruginosa

This study investigates the anti-pathogenic effects of the polyherbal formulation Enteropan against multidrug-resistant Pseudomonas aeruginosa, identifying molecular mechanisms and potential drug targets.

Protein generation with evolutionary diffusion: sequence is all you need

This paper introduces EvoDiff, a diffusion model that generates diverse, high-fidelity proteins in sequence space, overcoming limitations of structure-based models.

Identifying molecular targets of a colloidal nanosilver formulation (Silversol) in multidrug resistant Pseudomonas aeruginosa

The paper investigates the molecular targets of Silversol, a colloidal nanosilver formulation, in multidrug-resistant P. aeruginosa, identifying key genes involved in nitrogen metabolism and denitrification as potential targets.

Network analysis for identifying potential anti-virulence targets through whole transcriptome analysis of Pseudomonas aeruginosa and Staphylococcus aureus exposed to certain anti-pathogenic polyherbal formulations

Direct Imaging of Liquid Domains in Membranes by Cryo Electron Tomography

This paper develops two methods to directly image and quantify submicron liquid domains in membranes using cryo-electron tomography, enabling analysis under native conditions.